In an OGTT interpretation, what value combination indicates diabetes mellitus?

In an OGTT interpretation, what value combination indicates diabetes mellitus?

• A. Normal
• B. Diabetes mellitus
• C. Addison disease
• D. Hyperinsulinism

Answer: (B)

In an oral glucose tolerance test, diabetes is diagnosed when the two-hour plasma glucose value after consuming 75 g of glucose rises to 200 mg/dL (11.1 mmol/L) or higher. This cutoff shows that the body cannot regulate glucose effectively after a glucose challenge. Normal two-hour values are below 140 mg/dL, and 140–199 mg/dL indicates impaired glucose tolerance, not diabetes. Addison disease and hyperinsulinism don’t meet this threshold on the OGTT, since Addison’s relates to cortisol deficiency and metabolic issues, while hyperinsulinism tends to cause low glucose. So the combination that indicates diabetes is a two-hour post-load glucose of 200 mg/dL or higher.

In an oral glucose tolerance test, diabetes is diagnosed when the two-hour plasma glucose value after consuming 75 g of glucose rises to 200 mg/dL (11.1 mmol/L) or higher. This cutoff shows that the body cannot regulate glucose effectively after a glucose challenge. Normal two-hour values are below 140 mg/dL, and 140–199 mg/dL indicates impaired glucose tolerance, not diabetes. Addison disease and hyperinsulinism don’t meet this threshold on the OGTT, since Addison’s relates to cortisol deficiency and metabolic issues, while hyperinsulinism tends to cause low glucose. So the combination that indicates diabetes is a two-hour post-load glucose of 200 mg/dL or higher.